Hill-Robertson Interference Reduces Genetic Diversity on a Young Plant Y-Chromosome

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Hill-Robertson Interference Reduces Genetic Diversity on a Young Plant Y-Chromosome.

X and Y chromosomes differ in effective population size (Ne ), rates of recombination, and exposure to natural selection, all of which can affect patterns of genetic diversity. On Y chromosomes with suppressed recombination, natural selection is expected to eliminate linked neutral variation, and lower the Ne of Y compared to X chromosomes or autosomes. However, female-biased sex ratios and hig...

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Adaptive Evolution Is Substantially Impeded by Hill–Robertson Interference in Drosophila

Hill-Robertson interference (HRi) is expected to reduce the efficiency of natural selection when two or more linked selected sites do not segregate freely, but no attempt has been done so far to quantify the overall impact of HRi on the rate of adaptive evolution for any given genome. In this work, we estimate how much HRi impedes the rate of adaptive evolution in the coding genome of Drosophil...

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ژورنال

عنوان ژورنال: Genetics

سال: 2017

ISSN: 1943-2631

DOI: 10.1534/genetics.117.300142